Case Evaluation

Fluvoxamine: Fluvoxamine FAQ

Fluvoxamine FAQ

Q: What is fluvoxamine?

A: Fluvoxamine is in a class of medicines called Selective Serotonin Reuptake Inhibitors (SSRIs). Fluvoxamine is a generic medicine used to treat obsessive-compulsive disorder (OCD).

Q: Has there been any recent news about fluvoxamine?

A: In July 2006, the FDA issued two alerts related to fluvoxamine. The first FDA alert announced the results of a study concerning the use of antidepressant medicines during pregnancy by mothers of babies born with a serious condition called persistent pulmonary hypertension of the newborn (PPHN). Click here for more information on this FDA alert. The second FDA alert states that a life-threatening condition called serotonin syndrome can occur when SSRIs (such as fluvoxamine) and medicines used to treat migraine headaches known as 5-hydroxytryptamine receptor agonists (triptans), are taken together. Click here for more information on this FDA alert. Over the last few years, the FDA has worked closely with the manufacturers of all marketed antidepressants (such as fluvoxamine) to fully evaluate the risk of suicidality in children, adolescents, and adults treated with these medications. Click here for more information.

Q: Who should not take fluvoxamine?

A: You should not take fluvoxamine if you take another drug that treats depression, called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI in the last 14 days. Taking these two drugs close in time can result in serious (and sometimes fatal) reactions including high body temperature, coma, and seizures (convulsions).

Q: Are there any serious health risks associated with fluvoxamine?

A: Harmful side effects may occur if you stop taking fluvoxamine suddenly. Your healthcare professional should slowly decrease your dose as necessary. Other risks of fluvoxamine use include an increased risk of having suicidal thoughts or actions, bleeding problems, mania, seizures, and sexual problems. There are also increased risks if you take fluvoxamine while you are or may become pregnant.

Q: Are there any side effects associated with fluvoxamine?

A: Side effects associated with fluvoxamine use include nausea, vomiting, upset stomach, difficulty sleeping, nervousness, shakiness, sweating, weakness, decreased appetite, and sleepiness.

Q: What should I tell my healthcare professional before he or she prescribes fluvoxamine?

A: It is important to tell your healthcare professional about all known medical conditions, especially if you have liver or kidney disease, or glaucoma. Also, tell your healthcare professional if you breast-feed or plan to breast-feed your baby.

Q: Can other medicines or foods affect fluvoxamine?

A: It is important to tell your healthcare professional about all prescription and non-prescription medicines, vitamins, and herbal supplements that you take. Medicines of special concern include certain benzodiazepines (treats anxiety), Mextil (treats heartbeat problems), theophylline (treats asthma), and warfarin (treats blood clots). Talk to your healthcare professional if you plan to drink alcohol while taking fluvoxamine.

Q: What should I do if I think I have been injured as a result of taking fluvoxamine?

A: If you or a loved one have experienced any dangerous symptoms or unusual medical conditions related to fluvoxamine use, you should first contact your doctor or other healthcare professional. You may also wish to meet with an experienced attorney to discuss your options and to protect your right to a legal remedy for any injuries caused by fluvoxamine use.

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