Case Evaluation

Paxil: Antidepressant Linked to Violent Behavior

Antidepressant Linked to Violent Behavior

September 12, 2006 Study participants who took the antidepressant Paxil (paroxetine) were twice as likely to have violent episodes as those who took a placebo, a British study concludes.

The GlaxoSmithKline drug is among a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), which prior research has linked to an increased risk of suicidal thoughts and behaviors.

The new study from researchers at Cardiff University and the Cochrane Centre is published on the Public Library of Science (PLoS) - Medicine Web site. The scientists studied data provided by several sources, including Glaxo, according to Britain's The Guardian newspaper.

"The new issues highlighted by these cases need urgent examination in all countries where antidepressants are widely used," the researchers wrote.

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